Photoelectrocatalysis (PEC), combining Photocatalysis (PC) and electrochemistry, is an environmentally friendly technology widely studied for the removal of organic and micropollutants in wastewater. PEC overcomes the high electron/hole recombination in PC process PEC is based on the use of a semiconductor photoelectrode and counter electrode connected by an external circuit in an electrolytic cell, the photoelectrode activated by irradiation and at the same time biased by a potential gradient. Several PEC reactors based on TiO2 photocatalyst and UV-A irradiation have been designed with different geometries and configurations for the removal of organic pollutants 1. However, these different designs are still under study at a lab-scale due to the various limitations, including high energy consumption and cost, energy loss during irradiation, low mass-transfer rate, electrode preparation difficulties, maintenance and high thickness of the immobilized film in the photoanode. This work presents a novel Photoelectrocatalytic cell based on channels sandwich configuration for the removal of organic pollutants from wastewater with improvement in the mass transfer, energy loss during irradiation, and cost (Fig.1). Further, COMSOL Multiphysics software (CFD) has been used to evaluate the effect of inlet pipe diameter (6.5 ,10 , and 17 mm) and the sandwich reactor channels width (10, and 17mm) on the flow velocity and regime inside the reactor, but no difference has been found with changing the inlet pipe diameter. Though, decreasing the channel width resulted in increasing the velocity from 0.15 m/s to 0.25 m/s, leading to higher pollutant mass transfer. Also, a particle tracing experiment was performed using COMSOL to evaluate the mean residence time inside the reactor. The mean residence time estimated from the simulation was 8.2s while the theoretical mean residence time was 7.5 s.